in a Monday Night Football matchup for Week 10 Mohamed Sanu Jersey , beginning at 8:15 p.m. ET on ESPN (live streaming via WatchESPN). The 49ers sit at 2-7 on the season, while the Giants sit at 1-7 — hardly the MNF matchup we’ve all been waiting for. That said, both teams have been exciting at times this season.The 49ers have had serious injuries hurt their team on both sides of the ball. They rank 22nd in the league in total defense, and are particularly bad at forcing turnovers, ranking 31st in the league with a turnover differential of minus-13. The Giants are ranked pretty low in that regard as well, but still much better than the 49ers at No. 23 in the league, or a minus-4 differential. In addition to their better turnover differential, the Giants also rank 16th in the league in total defense.On the offensive side of the ball, the 49ers are ranked about middle-of-the-pack at 14th overall, despite injuries to their starting and backup quarterbacks, plus several other starters on that side of the ball. New York ranks 22nd in the league in total offense.Nick Mullens will be the starting quarterback for the 49ers on Monday, after his debut in relief of the injured C.J. Beathard went well against the Raiders the last time out. Below is all you need to know to watch on Monday.Time, TV Authentic Ryan Schraeder Jersey , and streaming infoTime: 8:15 p.m. ETLocation: Levi’s Stadium, Santa Clara, Calif.TV: ESPNStreaming: WatchESPNOdds: The 49ers opened as narrow three-point favorites at home against the Giants.Giants vs. 49ers newsKeeping up the trend of injuries, the 49ers ruled out safety Jaquiski Tartt, wide receiver Pierre Garcon and linebacker Reuben Foster for Monday’s game.On the other hand, the Giants are coming off a bye week and only had three players listed on their final injury report, all of whom are expected to play on Monday.As noted above, the 49ers have announced that Nick Mullens will be starting in primetime against the Giants. That doesn’t mean it’s the end of the road for Beathard, however.One bright spot in an otherwise rough season for the 49ers has been the play of tight end George Kittle.The 49ers found their pass rush against the Raiders the last time out. The Giants aren’t great at protecting Eli Manning, so they may have another opportunity to have a big game.Both teams are seven-loss teams already, which means a head-to-head meeting between the two has serious NFL Draft implications. The folks at Big Blue View took a look at the 49ers’ offense and the unique approach they have to personnel. They’ve also got three things to watch for on Monday.Giants vs. 49ers predictionIn the Week 10 SB Nation expert picks, all of the seven making picks think the 49ers will win it, as does the OddsShark computer. To complete the picking shutout Youth Austin Hooper Jersey , the coin flip also landed on the 49ers.Dan Quinn: Devonta Freeman expected to play on Sunday against Steelers, Grady Jarrett out Watch out, Pittsburgh Steelers. The Atlanta Falcons might be getting their run game back. Unrelated, but their pass defense is also going from shambles to nonexistent.It feels weird to say this, but the team is actually getting a player back from injury.Head coach Dan Quinn suggested early reports that Devonta Freeman will be out for two to three weeks were inaccurate, and based on my calendar, that was about two to three weeks ago. Regardless, this is a huge boost to Atlanta. The Falcons have been nearly unstoppable on offense, but have failed to establish a dominant run game. Freeman’s elusiveness and vision may somehow open things up even more.Plus, it’ll just be great to see Freeman playing. He’s an absolutely fun player to watch.We were pretty confident that Grady Jarrett would miss time after the Falcons signed a new defensive tackle yesterday. Early indications have been the ankle injury isn’t terribly severe, but early indications from multiple severe injuries had been very optimistic this season. With Atlanta’s playoff chances quickly dwindling, the team needs to get their best defensive tackle back on the field in a hurry.